To complement the physical infrastructure, the co-location of researchers from a range of University of Melbourne departments from the diverse fields of science, engineering, medicine, dental and health sciences, encourages interaction amongst the 500 plus scientists, students, administrators and industry researchers located within the complex.

Among the researchers based at the institute are:

Federation Fellows: Professor Paul Mulvaney - Nanocrystal and Nanomechanics Laboratories, Professor Ary Hoffman - Environmental Stress and Adaptation Laboratories & Professor Michael Parker - Structural Biology 

Laureate Professor Andrew Holmes - Chemical Synthesis Laboratories

Fellows of the Australian Academy of Science: Professor Tony Bacic - Director, Bio21 Institute, Professor Paul Mulvaney - Nanocrystal and Nanomechanics Laboratories, Professor Michael Parker - Structural Biology & Professor Andrew Holmes - Chemical Synthesis Laboratories