Michael Parker is a University of Melbourne Honorary Professorial Fellow affiliated with the Bio21 Institute.
The focus of his research is to understand the three-dimensional structures of medically important proteins using X-ray crystallography. Particularly proteins that play a role in infection (bacterial, parasitic or viral), cancer and neurobiology (e.g. Alzheimer's disease, epilepsy).
The structures that result provide a detailed understanding of how each protein works and how it contributes to disease. Most importantly, the structures can be used to discover drugs using computational approaches. Our work is supported by labs that specialise in protein expression, purification and electrophysiology.
Techniques include: Protein X-ray crystallography; structure-based drug design; electrophysiology; cloning, expression and purification of proteins
Professor Michael Parker is Associate Director of St. Vincent's Institute of Medical Research in Melbourne where he is Head of the Biota Structural Biology Laboratory. He is an Australian Research Council Federation Fellow, a National Health and Medical Research Council Honorary Fellow and is a Professorial Fellow of Melbourne University. After obtaining his D. Phil. in protein crystallography from Oxford University, Michael took up the post of staff scientist at the European Molecular Biology Laboratory in Germany. In 1991 Michael returned to Australia as a Wellcome Trust Senior Research Fellow to re-establish a protein crystallography laboratory at St. Vincent's. The work of the laboratory is internationally recognised with the determination of more than seventy crystal structures including those of membrane-associating proteins, detoxifying enzymes and protein kinases. This work has provided insights into a number of diseases such as cancer, bacterial and viral infections, and neurological diseases such as Alzheimer's disease. His work has been recognised with numerous awards including the 1999 Gottschalk Medal of the Australian Academy of Science and the GE Healthcare Bio-Sciences Award of the Australian Society for Biochemistry and Molecular Biology in 2004.
T: (+61 3) 8344 2500 or
T: (+61 3) 9288 2499
On this page