Mass Spectrometry

Agilent Ion Trap Mass Spectrometer LC/MSD Trap XCT Plus coupled to an Agilent 1100 series HPLC-ChipMass Spectrometry has emerged as a core analytical chemistry platform for proteomics and metabolomics.  Proteomics determines the structure and regulation of individual proteins. Metabolomics defines the chemical state of cells and changes in cell metabolism that occur in response to regulators, stress and test compounds.

The Institute's mass spectrometry capability includes 12 instruments which cover a range of applications including:

  • High accuracy determination of molecular mass of naturally occurring proteins, nucleic acids and metabolites, as well as chemically synthesised molecules
  • Protein sequencing by fragmentation analysis
  • Detection of individual molecular species in molecular profiling of cells and animal test systems
  • Validation of chemical synthesis and definition of chemically diverse metabolites requiring a variety of ionization techniques.

Accessing the Mass Spectrometers

To access the mass spectrometers contact the Research Transfer Facility Manager, Denis Scanlon.  Users will only be granted access after they have attended a formal training session.

Contact:

Dr Denis Scanlon 

Research Transfer Facility Manager

T: (+61 3) 8344 2206

E: deniss@unimelb.edu.au